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677,678 In another case, an enzyme has evolved that catalyzes a different reaction that eliminates the requirement for one or more other reactions within the same pathway, establishing an “alternative route.” 679 Metalloenzyme paralogs are a specialized type of nonorthologous displacement where an enzyme evolves to catalyze the same reaction as an obligatory Zn II -dependent enzyme, for example, but is characterized by a relaxed metal cofactor specificity profile or uses no metal at all

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CohBar Announces CB4211 Phase 1a/1b Results Selected for Late Breaker Presentation at The Liver Meeting 2021 | FirstWord Pharma Updated Oct 2021