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Infection of the cells with HSV-2 or stimulation with the TLR9 ligand ODN1826 led to accumulation of CCL5 and IFN-α/β in the culture supernatants of the cells expressing AdV-vector and this response was significantly decreased in cells expressing Adv-Grx (Figure 4C, D)

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The main nutrients required for Phase I include: B-vitamins (B2, 3, 6, 9, and 12) Magnesium & Zinc Glutathione Antioxidants – vitamin E, C, and selenium Phase II detoxification acts to safely package and neutralize the reactive compounds generated during Phase I