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Abbreviations ROS Reactive oxygen species UV Ultraviolet radiation DHICA Dihydroxyindole carboxylic acid TRP-2 Tyrosinase-related protein-2 8-OxodG 8-oxodeoxyguanosine BER Base excision repair ACTH Adrenocorticotropic hormone MC1R Melanocortin 1 receptor HO-1 heme Oxygenase-1 NAC N-acetylcysteine iNOS inducible nitric oxide synthase Footnotes Conflict of interest: The authors declare no conflict of interest