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These MAIT cells have a semi-invariant T-cell receptor TCRα (TRAV1-2–TRAJ33) β (TRBV20-TRBV6) and can be activated upon recognition of the riboflavin derivatives 5-OP-RU, 5-OE-RU, or RL-6,7-diMe bound to Major Histocompatibility complex class 1 related (MR1) protein, which is ubiquitously expressed on the cell surface of epithelial cells and immune cells 187

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