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Both reactions are initiated by a nucleophilic attack of the more N-terminal cysteinyl residue, which is characterized by a particularly low pK a value ≤ 5 [66,68,69,70], on the target disulfide

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A more extensive, longer-term study found that patients with mild cognitive impairment scored better on the Mini-Mental Status Exam and the Sleep Disorders Index when taking melatonin [106]