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Namely, in all these circumstances (L-NAME-non-responsive), L-NAME antagonized an L-arginine beneficial effect (NO-system immobilization) while BPC 157 co-administration restated a beneficial effect in the L-NAME+L-arginine rats (NO-system immobilization), and thereby, in both circumstances, the L-NAME+L-arginine+BPC 157 rats, BPC 157 counteracted NO-system immobilization [8]