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DHA not only reduces GSH to GSSG but also inactivates GPX4 directly, facilitating LPO accumulation and cell ferroptosis collaboratively (Figure 5E)

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Both are once-weekly amylin receptor agonists, but eloralintide is selective for the amylin receptor while cagrilintide also activates the calcitonin receptor, making it a dual amylin and calcitonin receptor agonist