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CeO 2 NPs (60 mg/kg, i.p., daily for 4 weeks) offer protection against PIPN in rats since they significantly increased myelin protein zero (MPZ) expression, decreased the MDA levels, and reversed the histopathological changes in sciatic nerves and lumbar spinal cord caused by OXA

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The findings of these studies indicate that glutathione therapy could represent a possible therapeutical tool in cases where ROS or exposure to toxins is the probable cause of infertility.