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Importantly, the expression of tumor suppressor protein P53 occurred earlier in the Gstp1/2 −/− regenerating livers with a sharp induction at 24 and 36 h while in the WT livers its expression mainly detected at 40 and 44 h was much lower

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The above-mentioned approach of functional MRS may also be helpful as it may reflect better the immediacy of fatigue and PEM, characteristic for ME/CFS